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Neurotransmitters: Noradrenaline

Abbigail Higgins

Noradrenaline Production and Packaging

Noradrenaline, also known as Norepinephrine, is a critical neurotransmitter for many brain functions. Before we can get too far into its neurological interactions, it is important to understand how we get noradrenaline in the body. Noradrenaline is a part of a chain of reactions (pictured bellow) that takes L-Tyrosine to Epinephrine. Because of this chain, the quantities of Norepinephrine are highly impacted by the levels of L-Tyrosine, L-DOPA, Dopamine, and Epinephrine. Changes in any of the molecule or enzyme concentrations will slightly alter the equilibrium (or the point where

Diagram showing the steps in the synthesis of catecholamine neurotransmitters.

 

Norepinephrine Receptors

 

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Alpha 1 receptors

 

Alpha 2 receptors

 

Beta 1 receptors

 

Beta 2 receptors

 

Norepinephrine Re-uptake and Removal

 

License

Developing Expertise in Neuroscience Copyright © by Jim Hutchins; Aliyah Grijalva; Avalon Marker; Canyon Madsen; Kobe Christensen; Lance Castro; Lindsey Aune; Caleb Bevan; Ryan Johnson; Misty Allen; and Tess Johnson. All Rights Reserved.