Connections Between the Neuronal Membrane and Extracellular Matrix

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In between the space of the cells in our brain is what is called the extracellular matrix. This is a gel like substance that functions as the “glue” of neurons holding them in place and organizing them. It composed of a network of proteins and carbohydrates specifically collagens, elastins, proteoglycans, fibronectins, laminins, and integrins.

Collagen is a major fibrous protein that acts as a scaffold for cells.

Elastin is also a fibrous tissue that provides elasticity.

Proteoglycans are large molecules made from protein and attached sugar chains called glycoaminoglycans. It serves to fill space, resist compression, and act as a reservoir for growth factors and other signaling molecules. 

https://pmc.ncbi.nlm.nih.gov/articles/PMC2675146/

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