Question 3: Do the results provide an answer to my PICOT question that will help me care for my patient in this setting?
This question is also known as clinical significance. Just because something has statistical significance doesn’t mean that it will be clinically significant to your patient population. In determining if it is clinically significant to your patient, you need to consider the following questions, many of which rely on your clinical expertise and understanding of your patient population.
Do the results apply to my patient?
First, you need to assess whether your patient or patient population is similar to those in the study. There are likely to be differences, but you must determine what the important differences are and if it will impact the effectiveness on your patient population.
For example, say you reviewed a study that demonstrated weekly group education classes were highly effective in helping control blood sugar fluctuations in patients newly diagnosed with type I diabetes. When asking how the results apply to your patient population, you first determine that your clients are also newly diagnosed with type I diabetes. If they aren’t newly diagnosed, the intervention may not produce the same results as those experienced by study participants. When you look at how the populations differ, you note that your patient population is located in a rural setting with limited access to care and that the study population in the published study was located in a major metropolitan city. The results of the original study may be important and meaningful, but due to some differences, it may not help you care for the patients in your setting.
What are the risks and benefits of treatment?
In some studies, researchers are able to carefully monitor and control the risks. In clinical settings, we may not be able to provide monitoring or control for side effects in the same manner as the original study, and the risks may outweigh the benefits for your patient population.
Is the treatment feasible in my clinical setting?
Using our type 1 diabetes example, the study may have found that weekly educational sessions helped to control blood sugar levels, but given the financial costs and available resources at your facility, you may not be able to offer weekly group education sessions.
What are my patient’s values and expectations for the outcome?
Using our same example, if you have a patient who is independent and introverted, group education sessions may not be consistent with these values, even though the intervention was shown to be effective. If your patient is unlikely to attend, it won’t be a helpful intervention for them.