Mechanisms of Air Movement

Objective 5

Define pulmonary ventilation, inspiration, and expiration. Define: Boyle’s Law. Explain the application of Boyle’s Law to inspiration and expiration. State the pressures in the structures of the respiratory system during inspiration and expiration.

 

Diagram showing the process of inspiration and expiration.

Let’s start by getting familiar with some more pulmonary terminology. Having a clear understand of what each word means will be important when describing and understanding the respiratory system.

Respiration: The process of gas exchange in the body.

Pulmonary Ventilation: The inhalation and exhalation of air. This involves the exchange of air between the atmosphere and the alveoli of the lungs.

Inspiration (inhalation): Movement of air into the lungs from the atmosphere.

    • Active process requiring muscle action

Expiration (exhalation): Movement of air out of the lungs into the atmosphere.

    • Passive process during quiet breathing due to the elastic recoil of the lungs
    • Active (muscle help) during vigorous exercise or certain disease conditions causing difficult expiration (e.g. chronic obstructive pulmonary diseases)

The Kinetic Molecular Theory

Animated demonstration of the kinetic molecular theory.

 

Let’s shift our attention to two important physics laws and the principles behind these laws that will help us understand respiration. The idea that gas molecules are like a bunch of little billiard balls zipping around and colliding with each other is called by the rather fancy name The Kinetic Molecular Theory. There are five principles in the theory:

 

  1. Diagram explaining how collisions between molecules and the wall of a container leads to the concept of pressure.There is a lot more space between gas particles than the gas particles themselves occupy.
  2. Particles move in a straight line until they collide. They move in different directions and have different speeds.
  3. The particles in a gas don’t interact with each other much, if at all.
  4. When particles collide, all the energy goes into bouncing, and none is absorbed by the particle.
  5. The average speed of the particles is related to the temperature.

In the 19th century, a number of scientists postulated gas laws. These laws were “absorbed” into the Kinetic Molecular Theory but we still learn them by the name of the person who stated them first.

Boyle’s Law

Illustration of Boyle's Law.

Pressure is the number of collisions with the wall of the container. Remember temperature is the average speed of the molecules.

Boyle’s Law says that pressure times volume is a constant at constant temperature. Human bodies are at a constant temperature of 37°C.

If volume goes down, pressure goes up. (If you press on a closed syringe, it’s volume decreases as you feel the pressure increase.)

If volume goes up, pressure goes down. (That is, there is more room between the molecules and fewer collisions.)

Diagram of the principles underlying Boyle's Law.

Boyle’s law has a direct application to the principles governing inspiration and expiration. During inspiration, contraction of the diaphragm and external intercostals muscles increase the volume of the thoracic cavity. As we just learned, as the volume increases, pressure decreases. The pressure in the thoracic cavity is now slightly less than atmospheric pressure. Recall that diffusion operates because molecules move from where they are at higher concentration to where they are at lower concentration. Because the molecules are at higher concentration when pressure increases, molecules move from regions of high pressure (high concentration) to regions of low pressure (low concentration).

Diagram of the changes in volume and pressure in the thoracic cavity during inspiration and expiration.

During deep, labored breathing, additional muscles are used to further enlarge the thoracic cavity. The accessory muscles include the sternocleidomastoid which elevates the sternum, the scalene muscles and pectoralis minor which elevate ribs.

Illustration showing the pump handle action of the ribcase during inspiration.

 

 

During inhalation the lifting of the sternum acts as the handle of a pump while the ribs elevate up and out like the handles of a bucket.

 

 

Diagram comparing the pressures in various parts of the thoracic cavity during breathing.

Exhalation is a passive process during quiet breathing. Elastic recoil of the chest wall and lungs causes the volume in the thoracic cavity to decrease. As the volume decreases, the pressure increases. Pressure is now higher in the thoracic cavity than atmospheric air and air flows out from high to low pressure.

During forced exhalation, abdominal muscles and the internal intercostals can contract and further decrease the volume of the thoracic cavity and increase the pressure.

Clinical Connection

Pneumothorax

Air may leak into the pleural cavity from trauma to the lung or a spontaneous rupture of a bleb, a weak spot on the lung. Since the leak prevents a difference in pressure from developing, the lung does not fully inflate and a pneumothorax, or collapsed lung, may occur. Physicians treat a pneumothorax by placing a chest tube between the ribs in the wall of the thoracic cavity. This allows the air to flow out. The tube is then removed or sealed off and the hole in the chest wall repaired so the lungs can spontaneously re-inflate.
Composite image showing a diagram and X-ray of a pneumothorax.

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Integrated Human Anatomy and Physiology Part 2 Copyright © by Jim Hutchins; Travis Price; Justin Burr; Maddison Johnston; Pamela Silberman; Jeffery Speth; Jordan West; Lyndsey Gremillion; and Misty Allen is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License, except where otherwise noted.

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